Species: Hu, Mu, Rt
Applications: IHC
Host: Rabbit Polyclonal
Species: Hu, Rt
Applications: WB
Host: Rabbit Polyclonal
Species: Hu
Applications: WB
Host: Rabbit Polyclonal
Species: Hu
Applications: AC
Description
Essential bifunctional enzyme that catalyzes both the N-deacetylation and the N-sulfation of glucosamine(GlcNAc) of the glycosaminoglycan in heparan sulfate. Modifies the GlcNAc-GlcA dissacharide repeating sugar backboneto make N-sulfated heparosan, a prerequisite substrate for later modifications in heparin biosynthesis. Has lowdeacetylase activity but high sulfotransferase activity
Bioinformatics
| Uniprot |
Human Human Human |
| Product By Gene ID |
64579 |
| Alternate Names |
- bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 4
- EC 2.8.2.8
- Glucosaminyl N-deacetylase/N-sulfotransferase 4
- HSST4
- N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 4
- NDST-4
- N-heparan sulfate sulfotransferase 4
- N-HSST 4
- NHSST4
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