NCKIPSD Products

Description

The protein encoded by this gene is localized exclusively in the cell nucleus. It plays a role in signal transduction, and may function in the maintenance of sarcomeres and in the assembly of myofibrils into sarcomeres. It also plays an important role in stress fiber formation. The gene is involved in therapy-related leukemia by a chromosomal translocation t(3;11)(p21;q23) that involves this gene and the myeloid/lymphoid leukemia gene. Alternative splicing occurs in this locus and two transcript variants encoding distinct isoforms have been identified.

Bioinformatics

Entrez	51517 Human
Uniprot	NP_909119.1 Human
Product By Gene ID	51517
Alternate Names	54 kDa vimentin-interacting protein 90 kDa SH3 protein interacting with Nck AF3p21 AF3P21DIP-1 dia interacting protein Dia-interacting protein 1 diaphanous protein interacting protein Diaphanous protein-interacting protein DIP DIP1 MGC23891 NCK interacting protein with SH3 domain ORF1 SPIN90VIP54 WASLBP WASP-interacting SH3-domain protein WISHSH3 adapter protein SPIN90 Wisk90 kDa