NCKIPSD Products

Description

NCKIPSD is encoded by this gene is localized exclusively in the cell nucleus. It plays a role in signal transduction, and may function in the maintenance of sarcomeres and in the assembly of myofibrils into sarcomeres. It also plays an important role in stress fiber formation. The gene is involved in therapy-related leukemia by a chromosomal translocation t(3;11)(p21;q23) that involves this gene and the myeloid/lymphoid leukemia gene. Alternative splicing occurs in this locus and two transcript variants encoding distinct isoforms have been identified.

Bioinformatics

Uniprot	NM_016453 Human Q9NZQ3 Human NP_909119 Human NP_909119.1 Human
Product By Gene ID	51517
Alternate Names	AF3p21 54 kDa vimentin-interacting protein Wisk90 kDa diaphanous protein interacting protein Diaphanous protein-interacting protein dia interacting protein Dia-interacting protein 1 MGC23891 WASLBP DIP ORF1 WASP-interacting SH3-domain protein DIP1 WISHSH3 adapter protein SPIN90 SPIN90VIP54 AF3P21DIP-1 90 kDa SH3 protein interacting with Nck NCK interacting protein with SH3 domain

Diseases related to NCKIPSD

Discover more about diseases related to NCKIPSD.

Wiskott-aldrich Syndrome
Therapy-related Leukemia
Tissue Adhesions
Leukemia
Immunologic Deficiency Syndromes
Neoplasms
Acute Monocytic Leukemia
Stomach Neoplasms
Neoplasm Metastasis
Melanoma
Neoplasms, Second Primary
M5b Acute Differentiated Monocytic Leukemia
Glioma
Hypoxia
Tumor Angiogenesis
Malignant Neoplasms
Therapy-related Acute Myeloid Leukemia
Aids-associated Nephropathy

Pathways for NCKIPSD

View related products by pathway and learn more about each of the pathways below.

Cell Motility
Cell Adhesion
Cell Migration
Endocytosis
Clathrin-mediated Endocytosis
Localization
Tube Formation
Synaptic Transmission
Cytokinesis
Synaptic Vesicle Endocytosis
Phagocytosis
Cellular Localization
Cell Growth
Angiogenesis
Exocytosis
Viral Replication

PTMs for NCKIPSD

Learn more about PTMs related to NCKIPSD.

Phosphorylation
Cleavage

Bioinformatics Tool for NCKIPSD

Discover related pathways, diseases and genes to NCKIPSD. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.