NCK1 Products

Antibodies
NCK1 Antibody (714506)
NCK1 Antibody (714506)
MAB7008
Species: Hu
Applications: WB, ICC
Host: Mouse Monoclonal
NCK1 Antibody (5B7)
NCK1 Antibody (5B7)
NBP2-37490
Species: Hu, Pm
Applications: WB, ELISA, Flow, IHC
Host: Mouse Monoclonal
NCK1 Antibody
NCK1 Antibody
AF7008
Species: Hu
Applications: WB
Host: Goat Polyclonal
Lysates
NCK1 Overexpression Lysate (D ...
NCK1 Overexpression Lysate (Denatu...
H00004690-T01
Species: Hu
Applications: WB
NCK1 Overexpression Lysate (N ...
NCK1 Overexpression Lysate (Native)
NBP2-10428
Applications: WB
Proteins
NCK1 Recombinant Protein
NCK1 Recombinant Protein
NBP1-45253
Species: Hu
Applications: PAGE
RNAi
NCK1 RNAi
NCK1 RNAi
H00004690-R01
Species: Hu

Description

Nck is a ubiquitously expressed adaptor protein consisting of one SH2 and three SH3 Src homology domains. Stimulation by epidermal growth factor (EGF) or platelet-derived growth factor (PDGF) leads to phosphorylation of Nck on tyrosine, serine and threonine residues. Overexpression of Nck resulted in transformation of NIH 3T3 and 3Y1 rat fibroblast (1-2). Additionally, Nck has been shown to associate with BLNK, PLCG1 and VAV1 in a B-cell antigen receptor-dependent fashion and may play a role in linking tyrosine and serine/threonine kinase pathways within the cell (2).

Bioinformatics

Uniprot Human
Human
Human
Human
Product By Gene ID 4690
Alternate Names
  • cytoplasmic protein NCK1
  • Nck-1
  • MGC12668
  • non-catalytic region of tyrosine kinase
  • SH2/SH3 adaptor protein NCK-alpha
  • nck-1
  • NCKalpha
  • NCKNCK tyrosine kinase
  • NCK adaptor protein 1melanoma NCK protein

Research Areas for NCK1

Find related products by research area and learn more about each of the different research areas below.

Cancer
Cell Cycle and Replication

PTMs for NCK1

Learn more about PTMs related to NCK1.

Phosphorylation
Ribosylation
Myristoylation

Bioinformatics Tool for NCK1

Discover related pathways, diseases and genes to NCK1. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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