Species: Hu, Mu, Rt, Ha
Applications: WB, ICC/IF, IHC, IP, MA
Host: Mouse Monoclonal
Species: Hu
Applications: Flow, ICC/IF, IHC
Host: Rabbit Polyclonal
Species: Mu, Rt
Applications: WB, ICC/IF
Host: Rabbit Polyclonal
Species: Hu
Applications: WB, ELISA, MA, AP
Description
Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. It is a tetrodotoxin-sensitive Na(+) channel isoform. Plays a role in pain mechanisms, especially in the development of inflammatory pain (from SwissProt).
Bioinformatics
| Entrez |
Human
|
| Uniprot |
Human
|
| Product By Gene ID |
6335 |
| Alternate Names |
- ETHA
- FEB3B
- hNE-Na
- Nav1.7
- NENA
- NE-NA
- NENAVoltage-gated sodium channel subunit alpha Nav1.7
- Neuroendocrine sodium channel
- Peripheral sodium channel 1
- PN1
- PN1hNE-Na
- SCN9A
- sodium channel protein type 9 subunit alpha
- Sodium channel protein type IX subunit alpha
- sodium channel, voltage-gated, type IX, alpha subunit
- voltage-gated sodium channel alpha subunit Nav1.7
- voltage-gated, type IX, alpha polypeptide
|
Research Areas for Nav1.7
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CancerNeuroscience
