NACA1 Products

Description

Prevents inappropriate targeting of non-secretory polypeptides to the endoplasmic reticulum (ER). Binds to nascent polypeptide chains as they emerge from the ribosome and blocks their interaction with the signal recognition particle (SRP), which normally targets nascent secretory peptides to the ER. Also reduces the inherent affinity of ribosomes for protein translocation sites in the ER membrane (M sites). May act as a specific coactivator for JUN, binding to DNA and stabilizing the interaction of JUN homodimers with target gene promoters

Bioinformatics

Uniprot	NP_001106673 Human
Product By Gene ID	4666
Alternate Names	Allergen Hom s 2 Alpha-NAC alpha-NAC MGC117224 NACA1 NAC-alpha nascent polypeptide-associated complex alpha subunit nascent polypeptide-associated complex subunit alpha nascent-polypeptide-associated complex alpha polypeptide