Myosin light chain kinase Products

Antibodies
Myosin light chain kinase Ant ...
Myosin light chain kinase Antibody
NBP1-87744
Species: Hu, Mouse, Rat
Applications: WB, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
Myosin light chain kinase Ant ...
Myosin light chain kinase Antibody
H00004638-D01P
Species: Hu
Applications: WB, ELISA, PLA
Host: Rabbit Polyclonal
Myosin light chain kinase Ant ...
Myosin light chain kinase Antibody
32180002
Species: Hu
Applications: ELISA, IHC, IHC-P
Host: Rabbit Polyclonal
Lysates
Myosin light chain kinase Ove ...
Myosin light chain kinase Overexpr...
H00004638-T01
Species: Hu
Applications: WB
Myosin light chain kinase Ove ...
Myosin light chain kinase Overexpr...
NBP2-05825
Applications: WB
Proteins
Myosin light chain kinase Rec ...
Myosin light chain kinase Recombin...
H00004638-P01
Species: Hu
Applications: WB, ELISA, PA
Myosin light chain kinase Par ...
Myosin light chain kinase Partial ...
H00004638-Q01
Species: Hu
Applications: WB, ELISA, PA
Myosin light chain kinase Rec ...
Myosin light chain kinase Recombin...
NBP1-87744PEP
Species: Hu
Applications: AC
RNAi
Myosin light chain kinase RNA ...
Myosin light chain kinase RNAi
H00004638-R16
Species: Hu
Myosin light chain kinase RNA ...
Myosin light chain kinase RNAi
H00004638-R14
Species: Hu
Myosin light chain kinase RNA ...
Myosin light chain kinase RNAi
H00004638-R10
Species: Hu

Description

Myosin light chain kinase (MLCK) is a serine/threonine kinase that belongs to CaM Kinases (Ca++/Calmodulin-dependent protein kinases) family. MLCK is involved in the regulation of myosin activity during smooth muscle contraction. At increased level of Ca2+, rapid binding of Ca2+ to Calmodulin (CaM) occurs, triggering MLCK activation. Once activated, MLCK phosphorylates myosin light chain (MLC) and leading to cross-bridges cycling and generation of the contractile force (1). MLCK has been implicated in the regulation of endothelial and vascular permeability and in signaling pathway which leads to fibroblast apoptosis (2).

Bioinformatics

Uniprot Human
Human
Human
Human
Human
Human
Product By Gene ID 4638
Alternate Names
  • FLJ12216
  • EC 2.7.11
  • DKFZp686I10125
  • Telokin
  • EC 2.7.11.18
  • telokin
  • KRP
  • smooth muscle myosin light chain kinase
  • Kinase-related protein
  • smooth muscle
  • light polypeptide kinase
  • MYLK1
  • MSTP083
  • MLCK1
  • MLCKMLCK210
  • MLCK108
  • myosin light chain kinase

Research Areas for Myosin light chain kinase

Find related products by research area and learn more about each of the different research areas below.

Protein Kinase

PTMs for Myosin light chain kinase

Learn more about PTMs related to Myosin light chain kinase.

Phosphorylation
Methylation

Bioinformatics Tool for Myosin light chain kinase

Discover related pathways, diseases and genes to Myosin light chain kinase. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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