Description
Mycobacterium tuberculosis antigen 85 is a complex of three related gene products of 30-31 kDa, Ag85A, B and C. These proteins are responsible for the high affinity of mycobacteria to fibronectin. All three proteins possesses a mycolyltransferase activity - which is required for the biogenesis of trehalose dimycolate (cord factor), a dominant structure necessary for maintaining cell wall integrity. Thus all three proteins are involved in the final stages of mycobacterial cell wall assembly.
Bioinformatics
| Alternate Names |
- 85 A
- 85A
- Ag85A
- Antigen 85 A
- Antigen 85 complex A
- Antigen 85 complex A
- Antigen 85A
- Fbp A
- FbpA
- Fibronectin Binding protein A
- Mpt 44
- Mpt44
- Mycobacterium tuberculosis antigen 85A
- Mycolyl transferase 85 A
- Mycolyl transferase 85A
- Rv3804c
- Secreted antigen Ag85A
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