mut-7 Products

Antibodies
mut-7 Antibody
mut-7 Antibody
NBP1-92155
Species: Hu
Applications: ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
mut-7 Antibody
mut-7 Antibody
NBP1-56477
Species: Hu
Applications: WB
Host: Rabbit Polyclonal
Proteins
mut-7 Recombinant Protein Ant ...
mut-7 Recombinant Protein Antigen
NBP1-92155PEP
Species: Hu
Applications: AC
RNAi
mut-7 RNAi
mut-7 RNAi
H00054932-R01
Species: Hu

Description

Chimera RNA interference (chimera RNAi) is process by which small interfering RNA/DNA chimera triggers the destruction of mRNA for the original gene. The discovery work, design, and application of chimera RNAi has been pioneered by Professor Kaoru Saigo and Dr. Kumiko Ui-Tei at the University of Tokyo. Chimera RNAi has many advantages over the conventional siRNAs. First, it has been demonstrated to have reliable knock-down for over 10,000 human genes. Because the human genome is composed of an intricate, genetic network, chimera RNAi's unique design has successfully obviated the off-target effects including microRNA-based influence. Another advantage of the chimera RNAi technology is its effectiveness at low concentrations (0.5nM to 5nM); only mRNA is destroyed so genomic genes are not affected. Finally, having both the sense and anti-sense strands consisting RNA/DNA chimera, it offers much greater compound stability for streamlining in vitro and in vivo assays and applications while minimizing interferon induction and other adverse reactions.

Bioinformatics

Uniprot Human
Product By Gene ID 54932
Alternate Names
  • EC 3.1
  • LOC54932
  • probable exonuclease mut-7 homolog
  • Exonuclease 3'-5' domain-containing protein 3
  • MGC74981
  • mut-7
  • MGC131904
  • FLJ20433
  • FLJ30442
  • exonuclease 3'-5' domain containing 3

Bioinformatics Tool for mut-7

Discover related pathways, diseases and genes to mut-7. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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