MTO1 Products

Description

This gene encodes a mitochondrial protein thought to be involved in mitochondrial tRNA modification. The encoded protein may also play a role in the expression of the non-syndromic and aminoglycoside-induced deafness phenotypes associated with a specific mutation in the mitochondrial 12S rRNA gene. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]. Transcript Variant: This variant (2) includes an additional in-frame exon compared to variant 1; it encodes isoform b which is longer than isoform a. The additional protein-coding exon contains Alu Sine repeat sequence.

Bioinformatics

Product By Gene ID	25821
Alternate Names	EC 1.1.1.40 EC 6.3.5 homolog of yeast Mto1 mitochondrial MTO1-3 mitochondrial translation optimization 1 homolog (S. cerevisiae) protein MTO1 homolog, mitochondrial