MST4 Products

Antibodies
MST4 Antibody (7H4)
MST4 Antibody (7H4)
H00051765-M02
Species: Hu, Rt
Applications: WB, ELISA, ICC/IF
Host: Mouse Monoclonal
MST4 Antibody
MST4 Antibody
NBP2-38882
Species: Hu, Mouse, Rat
Applications: ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
MST4 Antibody (2G6)
MST4 Antibody (2G6)
H00051765-M01
Species: Hu
Applications: WB, ELISA, ICC/IF
Host: Mouse Monoclonal
Antibody Pairs
MST4 Antibody Pair
MST4 Antibody Pair
H00051765-PW1
Species: Hu
Applications: WB, IP
Lysates
MST4 Overexpression Lysate (N ...
MST4 Overexpression Lysate (Native)
NBP2-07020
Applications: WB
MST4 Overexpression Lysate (D ...
MST4 Overexpression Lysate (Denatu...
H00051765-T01
Applications: WB
Proteins
MST4 Recombinant Protein Anti ...
MST4 Recombinant Protein Antigen
NBP2-38882PEP
Species: Hu
Applications: AC
MST4 Recombinant Protein
MST4 Recombinant Protein
P4728
Species: Hu
Applications: Func, PAGE
RNAi
MST4 RNAi
MST4 RNAi
H00051765-R02
Species: Hu

Description

Novel human Ste20-related kinase Mst4 is highly expressed in placenta, thymus, and peripheral blood leukocytes. Mst4 is biologically active in the activation of MEK/ERK pathway and in mediating cell growth and transformation (1). Wild type and C-terminally truncated forms of Mst4 can both induce apoptosis upon overexpression in mammalian cells that is abrogated by CrmA, suggesting involvement of Mst4 in the apoptotic machinery in mammalian cells (2). Mst4 was found to be expressed in prostate carcinoma tumor samples and cell lines. In addition, expression levels appeared to correlate with tumorigenicity and androgen receptor status of the cells. Mst4 kinase activity was stimulated significantly by epidermal growth factor receptor ligands, which are known to promote growth of prostate cancer cells (3).

Bioinformatics

Entrez Human
Uniprot Human
Human
Human
Product By Gene ID 51765
Alternate Names
  • EC 2.7.11
  • EC 2.7.11.1
  • serine/threonine-protein kinase MST4
  • STE20-like kinase MST4
  • serine/threonine protein kinase MST4
  • Mst3 and SOK1-related kinase
  • serine/threonine protein kinase MASK
  • MST-4
  • mammalian sterile 20-like 4
  • MASK
  • Serine/threonine-protein kinase MASK
  • Mammalian STE20-like protein kinase 4

Research Areas for MST4

Find related products by research area and learn more about each of the different research areas below.

Protein Kinase

PTMs for MST4

Learn more about PTMs related to MST4.

Phosphorylation
Cleavage
Reduction
Dephosphorylation

Bioinformatics Tool for MST4

Discover related pathways, diseases and genes to MST4. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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