MRPL22 Products

Description

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein that belongs to the L22 ribosomal protein family. A pseudogene corresponding to this gene is found on chromosome 4q. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]

Bioinformatics

Entrez	29093 Human
Uniprot	AAH12565 Human
Product By Gene ID	29093
Alternate Names	39S ribosomal protein L25, mitochondrial DKFZp781F1071 L22mt L25mt mitochondrial ribosomal protein L22 MRP-L22 MRPL25 MRP-L25HSPC158 RPML2539S ribosomal protein L22, mitochondrial