MRCL3 Products

MRCL3 [p Ser19, p Ser20] Anti ...
MRCL3 [p Ser19, p Ser20] Antibody
Species: Hu, Mu
Applications: WB, ELISA, IHC, IHC-P, IP
Host: Rabbit Polyclonal
MRCL3 [p Ser18] Antibody
MRCL3 [p Ser18] Antibody
Species: Hu, Mu, Rt
Applications: WB, IHC, IHC-P
Host: Rabbit Polyclonal
MRCL3 Antibody
MRCL3 Antibody
Species: Hu
Applications: WB
Host: Rabbit Polyclonal
MRCL3 Overexpression Lysate
MRCL3 Overexpression Lysate
Species: Hu
Applications: WB
Recombinant Human MRCL3 His P ...
Recombinant Human MRCL3 His Protein
Species: Hu
Applications: PAGE


The muscle myosins and hexomeric proteins consisting of two heavy chains and two pairs of light chains, the latter called essential (ELC) and regulatory (RLC). The light chains stabilize the long alpha helical neck of the myosin head (1). Human myosin light chain-2 (MYL2) is an important protein involved in the regulation of myosin ATPase activity in smooth muscle. In cardiac muscle, the precise role of MYL2 is not well understood; however, an increase in ventricular MYL2 is observed during myocardial hypertrophy in cardiac patients with valve stenosis (2). Familial hypertrophic cardiomyopathy (FHC) is an autosomal dominant disease caused by mutations in all of the major sarcomeric proteins, including the ventricular myosin regulatory light-chain (RLC). The Myosin RLC mutation has been associated with a rare variant of cardiac hypertrophy defined by mid-left ventricular obstruction due to papillary muscle hypertrophy. This mutation was later found to cause ventricular and septal hypertrophy (3).


Entrez Human
Uniprot Human
Product By Gene ID 10627
Alternate Names
  • MLCBMyosin RLC
  • MRCL3
  • MYL2B
  • myosin regulatory light chain 12A
  • Myosin regulatory light chain 2, nonsarcomeric
  • myosin regulatory light chain 3
  • myosin regulatory light chain MRCL3
  • Myosin regulatory light chain MRLC3
  • myosin, light chain 12A, regulatory, non-sarcomeric
  • myosin, light polypeptide, regulatory, non-sarcomeric (20kD)
  • RLC

Diseases related to MRCL3

Discover more about diseases related to MRCL3.

Malignant Neoplasms
Colonic Neoplasms
Malignant Tumor Of Colon
Tissue Adhesions

Pathways for MRCL3

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Cell Adhesion

PTMs for MRCL3

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Bioinformatics Tool for MRCL3

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