MPRA Products

Antibodies
MPRA Antibody
MPRA Antibody
NBP2-13731
Species: Hu
Applications: ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
Lysates
MPRA Overexpression Lysate (N ...
MPRA Overexpression Lysate (Native)
NBP2-04977
Applications: WB
Proteins
MPRA Recombinant Protein Anti ...
MPRA Recombinant Protein Antigen
NBP2-13731PEP
Species: Hu
Applications: AC
MPRA Recombinant Protein
MPRA Recombinant Protein
H00164091-G01
Species: Hu
RNAi
MPRA RNAi
MPRA RNAi
H00164091-R02
Species: Hu
Applications: RNAi, RNAi SP

Description

The steroid progesterone induces the resumption of maturation in oocytes via a nongenomic pathway through binding to a novel, membrane progestin receptor (mPR). This pathway inhibits adenylyl cyclase and reduces intracellular cAMP, and also activates mitogen-activated protein kinase to effect signal transduction pathways. Three distinct groups, designated alpha, beta and gamma, comprise this gene family. mPRalpha, also designated progestin and adipoQ receptor family member VII (PAQR7), consists of an extracellular N-terminus, an intracellular C-terminus, and seven transmembrane domains. It is expressed in ovary, testis, placenta, uterus and bladder. mPRbeta, also designated progestin and adipoQ receptor family member VIII (PAQR8), consists of eight putative transmembrane regions and an intracellular N-terminus that contains a leucine-rich motif. It is a 354 amino acid protein with a molecular mass of about 40 kDa and is expressed in brain and spinal cord. Both mPRalpha and mPRbeta may be G protein-coupled receptors and may be involved in oocyte maturation.

Bioinformatics

Entrez Human
Uniprot Human
Human
Human
Product By Gene ID 164091
Alternate Names
  • mPR alpha
  • MRPA
  • Progestin and adipoQ receptor family member 7
  • membrane progestin receptor alpha
  • mSR
  • MPRA2310021M12Rik
  • progestin and adipoQ receptor family member VIIPGLP

Pathways for MPRA

View related products by pathway and learn more about each of the pathways below.

Glucose Homeostasis
Secretion
Hormone Secretion

PTMs for MPRA

Learn more about PTMs related to MPRA.

Phosphorylation

Bioinformatics Tool for MPRA

Discover related pathways, diseases and genes to MPRA. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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