Species: Hu, Mu, Rt
Applications: WB, ICC/IF, IHC
Host: Rabbit Polyclonal
Species: Hu, Mu, Rt
Applications: WB, IHC
Host: Rabbit Polyclonal
Species: Hu, Mu, Rt
Applications: WB
Host: Rabbit Polyclonal
Species: Hu
Applications: WB
Species: Hu
Applications: AC
Description
The homeobox gene Hb9/Hlxb9, is expressed selectively by motor neurons (MNs) in the developing vertebrate CNS. Hb9, which encodes a factor central to MN development regulates neuronal fate by restricting expression of Lim3 and Even-skipped (Eve), two homeodomain (HD) proteins required for development of distinct neuronal classes. In the vertebrate CNS, HB9/MNR2 transcription factors are specifically expressed in all somatic motoneurons and are necessary to distinguish motoneurons from interneurons. Hb9 is also a transcription factor expressed in lymphoid and pancreatic tissue. In humans, HB9 mutation causes an autosomal dominant form of sacral agenesis.
Bioinformatics
| Product By Gene ID |
3110 |
| Alternate Names |
- HB9
- HLXB9motor neuron and pancreas homeobox protein 1
- homeobox HB9
- HOXHB9Homeobox protein HB9
- motor neuron and pancreas homeobox 1
- SCRA1homeo box HB9
|
Research Areas for MNX1/HLXB9
Find related products by research area and learn more about each of the different research areas below.
Cell BiologyNeuroscience
