Applications: WB, IHC
Host: Mouse monoclonal
Applications: WB, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
Applications: ELISA, ICC/IF, IHC-P
Host: Mouse Monoclonal
Applications: B/N, Ctrl
Applications: RNAi, RNAi SP
The myeloid cell nuclear differentiation antigen (MNDA) is detected only in nuclei of cells of the granulocyte-monocyte lineage. A 200-amino acid region of human MNDA is strikingly similar to a region in the proteins encoded by a family of interferon-inducible mouse genes, designated Ifi-201, Ifi-202, and Ifi-203, that are not regulated in a cell- or tissue-specific fashion. The 1.8-kb MNDA mRNA, which contains an interferon-stimulated response element in the 5-prime untranslated region, was significantly upregulated in human monocytes exposed to interferon alpha. MNDA is located within 2,200 kb of FCER1A, APCS, CRP, and SPTA1. In its pattern of expression and/or regulation, MNDA resembles IFI16, suggesting that these genes participate in blood cell-specific responses to interferons.
Bioinformatics Tool for MNDA
Discover related pathways, diseases and genes to MNDA. Need help? Read the Bioinformatics Tool Guide
for instructions on using this tool.