MMP21 Products

MMP21 Antibody (2F10)
MMP21 Antibody (2F10)
Species: Hu
Applications: WB, ELISA
Host: Mouse Monoclonal
MMP21 Antibody
MMP21 Antibody
Species: Mu
Applications: WB
Host: Rabbit Polyclonal
MMP21 Overexpression Lysate
MMP21 Overexpression Lysate
Species: Hu
Applications: WB
Recombinant Human MMP21 GST ( ...
Recombinant Human MMP21 GST (N-Ter...
Species: Hu
Applications: WB, ELISA, PA, AP


Matrix metalloproteinases (MMPs) play key roles in tissue remodelling under normal development and, especially, in diseases ranging from malignancies to stroke. Expression of MMP-21 is controlled uniquely by Pax and Notch transcription factors known to be critical for organogenesis. MMP-21 is expressed transiently in mouse embryogenesis and increased in embryonic neuronal tissues. Observations indicate that there is an important specific function for MMP-21 in embryogenesis, especially in neuronal cells (1). MMP-21 is expressed in various human fetal and adult tissues as well as in cancer cell lines. MMP-21 protein can also be detected in malignancies such as ovarian and colon carcinomas by immunohistochemical staining. Findings suggest that MMP-21 functions in embryogenesis and tumor progression (2). Results suggest that during development, MMP-21 expression is temporally and spatially tightly controlled. Unlike many classical MMPs, it is present in various normal adult tissues. Among epithelial MMPs, MMP-21 has a unique expression pattern in cancer (3).


Entrez Human
Uniprot Human
Product By Gene ID 118856
Alternate Names
  • EC 3.4.24
  • EC 3.4.24.-
  • matrix metallopeptidase 21
  • matrix metalloproteinase 21
  • matrix metalloproteinase-21
  • MMP-21

Pathways for MMP21

View related products by pathway and learn more about each of the pathways below.

Keratinocyte Differentiation
Secretory Pathway
Cell Proliferation
Skin Development

Research Areas for MMP21

Find related products by research area and learn more about each of the different research areas below.

Breast Cancer

Bioinformatics Tool for MMP21

Discover related pathways, diseases and genes to MMP21. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
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