MMP21 Products

Antibodies
MMP21 Antibody
MMP21 Antibody
NBP1-85980
Species: Hu, Mu, Rt, Mouse, Rat
Applications: WB, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
MMP21 Antibody (2F10)
MMP21 Antibody (2F10)
H00118856-M01-100ug
Species: Hu
Applications: WB, ELISA
Host: Mouse Monoclonal
Lysates
MMP21 Overexpression Lysate ( ...
MMP21 Overexpression Lysate (Native)
NBP2-05438
Applications: WB
Proteins
MMP21 Partial Recombinant Pro ...
MMP21 Partial Recombinant Protein
H00118856-Q01
Species: Hu
Applications: WB, ELISA, PA
MMP21 Recombinant Protein Ant ...
MMP21 Recombinant Protein Antigen
NBP1-85980PEP
Species: Hu
Applications: AC
RNAi
MMP21 RNAi
MMP21 RNAi
H00118856-R01
Species: Hu

Description

Matrix metalloproteinases (MMPs) play key roles in tissue remodelling under normal development and, especially, in diseases ranging from malignancies to stroke. Expression of MMP-21 is controlled uniquely by Pax and Notch transcription factors known to be critical for organogenesis. MMP-21 is expressed transiently in mouse embryogenesis and increased in embryonic neuronal tissues. Observations indicate that there is an important specific function for MMP-21 in embryogenesis, especially in neuronal cells (1). MMP-21 is expressed in various human fetal and adult tissues as well as in cancer cell lines. MMP-21 protein can also be detected in malignancies such as ovarian and colon carcinomas by immunohistochemical staining. Findings suggest that MMP-21 functions in embryogenesis and tumor progression (2). Results suggest that during development, MMP-21 expression is temporally and spatially tightly controlled. Unlike many classical MMPs, it is present in various normal adult tissues. Among epithelial MMPs, MMP-21 has a unique expression pattern in cancer (3).

Bioinformatics

Entrez Human
Uniprot Human
Human
Human
Product By Gene ID 118856
Alternate Names
  • EC 3.4.24
  • EC 3.4.24.-
  • matrix metalloproteinase-21
  • MMP-21
  • matrix metalloproteinase 21
  • matrix metallopeptidase 21

Pathways for MMP21

View related products by pathway and learn more about each of the pathways below.

Keratinocyte Differentiation
Secretory Pathway
Cell Proliferation
Gastrulation
Translation
Skin Development
Angiogenesis
Pathogenesis

Research Areas for MMP21

Find related products by research area and learn more about each of the different research areas below.

Breast Cancer

Bioinformatics Tool for MMP21

Discover related pathways, diseases and genes to MMP21. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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