Mind Bomb 2/MIB2 Products

Antibodies
Mind Bomb 2/MIB2 Antibody - B ...
Mind Bomb 2/MIB2 Antibody - BSA Free
NBP2-57751
Species: Hu, Mu, Rt
Applications: IHC
Host: Rabbit Polyclonal
Formulation Catalog # Availability Price  
Proteins
Recombinant Human Mind Bomb 2 ...
Recombinant Human Mind Bomb 2/MIB2...
H00142678-Q01
Species: Hu
Applications: WB, ELISA, MA, AP
Mind Bomb 2/MIB2 Recombinant ...
Mind Bomb 2/MIB2 Recombinant Prote...
NBP2-57751PEP
Species: Hu
Applications: AC

Description

MIB2/Skeletrophin is an actin-binding protein that bears two MIB/HERC2 domains, a ZZ-type zinc-finger domain, nine ankyrin repeats, and two RING-finger domains. The C-terminal RING domain has been found to have E3 ubiquitin ligase activity that mediates ubiquitination of the intracellular regions of the Notch receptor and its ligands to regulate Notch signaling. MIB2/Skeletrophin appears to be important to muscle development and may function as a suppressor of melanoma invasion.

Bioinformatics

Entrez Human
Uniprot Human
Product By Gene ID 142678
Alternate Names
  • E3 ubiquitin-protein ligase MIB2
  • EC 6.3.2
  • EC 6.3.2.-
  • EC 6.3.2.13
  • FLJ20648
  • FLJ41406
  • Mind bomb homolog 2
  • mindbomb homolog 2 (Drosophila)
  • Novel zinc finger protein
  • novelzin
  • Novelzin
  • Putative NF-kappa-B-activating protein 002N
  • SKD
  • Skeletrophin
  • Zinc finger ZZ type with ankyrin repeat domain protein 1
  • ZZ type with ankyrin repeat domain 1
  • ZZANK1

Research Areas for Mind Bomb 2/MIB2

Find related products by research area and learn more about each of the different research areas below.

Signal Transduction