Microsomal Glutathione S-transferase 1 Products

Description

The MAPEG (Membrane Associated Proteins in Eicosanoid and Glutathione metabolism) family consists of six human proteins, two of which are involved in the production of leukotrienes and prostaglandin E, important mediators of inflammation. Other family members, demonstrating glutathione S-transferase and peroxidase activities, are involved in cellular defense against toxic, carcinogenic, and pharmacologically active electrophilic compounds. This gene encodes a protein that catalyzes the conjugation of glutathione to electrophiles and the reduction of lipid hydroperoxides. This protein is localized to the endoplasmic reticulum and outer mitochondrial membrane where it is thought to protect these membranes from oxidative stress. Four transcript variants of this gene encode one protein isoform. [provided by RefSeq]

Bioinformatics

Product By Gene ID	4257
Alternate Names	glutathione S-transferase 12 GST12EC 2.5.1.18 MGC14525 MGST MGST-I microsomal glutathione S-transferase 1 Microsomal GST-1 Microsomal GST-I

Research Areas for Microsomal Glutathione S-transferase 1

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Cell Biology