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Metabotropic Glutamate Receptor 6 (mGluR6) is a member of the G protein-coupled receptor III family, linked to the inhibition of the cyclic AMP cascade. mGluR6 displays the highest sequence similarity to mGluR4 among the metabotropic receptor subtypes and inhibits the forskolin-stimulated cyclic AMP accumulation in CHO cells transfected with the cloned cDNA.
mGluR6 antibodies are most useful for G protein-coupled receptor research and metabolism studies.
