mGluR5/1 Products

Antibodies
mGluR5/1 Antibody (ST51-00)
mGluR5/1 Antibody (ST51-00)
NBP2-67508
Species: Hu, Mu, Rt
Applications: WB, Flow, ICC/IF, IHC, IHC-P, IP
Host: Rabbit Monoclonal
mGluR5/1 Antibody
mGluR5/1 Antibody
NB300-126
Species: Hu, Mu, Rt
Applications: WB, IHC, IHC-Fr
Host: Rabbit Polyclonal

Description

Glutamate is the main excitatory neurotransmitter in the brain. For many years it had been considered to act only on the ligand-gated receptor channels-termed NMDA, AMPA and kainate receptors that are involved in the fast excitatory synaptic transmission. Recently, glutamate has been shown to regulate enzymes producing second messengers via specific receptors coupled to G-proteins. These receptors are called metabotropic glutamate receptors. In expression systems, Group-I receptors, stimulate phospholipase C as revealed by an increase in phosphoinositide turnover, and Ca2+ release from internal stores. Group-II and -III receptors are coupled to the inhibition of adenylyl cyclase. The Group-I receptors include mGluR1a and mGluR5. The Group-II receptors in include mGluR2 and mGluR3.

Bioinformatics

Entrez Rat
Uniprot Rat
Product By Gene ID 2915
Alternate Names
  • mGluR5
  • mGlu5
  • GPRC1EMGLUR5metabotropic glutamate receptor 5
  • glutamate receptor, metabotropic 5

Pathways for mGluR5/1

View related products by pathway and learn more about each of the pathways below.

Chemotaxis
System Development
Nervous System Development
Cell Differentiation
Synaptic Transmission
Neurogenesis
Cell Growth
Central Nervous System Development

Research Areas for mGluR5/1

Find related products by research area and learn more about each of the different research areas below.

Metabotropic Glutamate Receptors
Neuronal Cell Markers
Neuroscience
Neurotransmission

PTMs for mGluR5/1

Learn more about PTMs related to mGluR5/1.

Phosphorylation

Bioinformatics Tool for mGluR5/1

Discover related pathways, diseases and genes to mGluR5/1. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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