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NL007). Before incubation with the primary antibody, tissue was subjected to heat-induced epitope retrieval using Antigen Retrieval Reagent-Basic (CTS013). Tissue was stained using DAB (brown) and counterstained with hematoxylin (blue). Specific staining was localized to cell surface of neurons in granular cell layer. Staining was performed using our protocol for Fluorescent IHC Staining of Paraffin-embedded Tissue Sections." class="big_lightbox" target="_blank">
Species: Hu Applications: Flow, IHC, CyTOF-ready Host: Mouse Monoclonal
The Metabotropic Glutamate Receptor GRM2 binds L-glutamate and has been linked to the inhibition of the cyclic AMP signaling cascade. GRM2 is involved in mediating the suppression of neurotransmission and in synaptogenesis and synaptic stabilization. Glutamatergic neurotransmission plays a role in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. GRM2 has been reported in various regions of the human and animal brain, as well as in rat eye and spinal cord. ESTs have been isolated from brain and testis libraries. Caution: GLUR2 refers to Ionotropic Glutamate Receptor 2, not to Metabotropic Glutamate Receptor 2 (mGLUR2).
![Flow Cytometry mGluR2 Antibody (421614) [Unconjugated]](http://images.novusbio.com/images/antibody/mGluR2_MAB46762_Flow_Cytometry_23932.jpg)
![Immunohistochemistry mGluR2 Antibody (421614) [Unconjugated]](http://images.novusbio.com/images/antibody/mab46762_human-mglur2-mab-clone-421614-immunohistochemistry-4122020141954.jpg)
