Species: Hu, Mu, Rt, Eq, Fi, Rb
Applications: WB, ELISA, IHC
Host: Mouse Monoclonal
Species: Hu, Rb
Applications: WB, ELISA
Host: Rabbit Monoclonal
Species: Ba
Applications: WB, ELISA
Host: Mouse Monoclonal
Description
Metallothioneins (MTs) are a class of ubiquitous, low molecular weight, cysteine-rich, metal binding proteins that function in the metabolism of zinc and copper. MT protects against exposure to toxic metals such as mercury and cadmium as well as a variety of other stress conditions. There are four mammalian MT isoforms: MT-I, -II, -III, -IV, each of which is encoded by individual genes. MT expression is induced by heavy metal cations, starvation, elevated temperature, lipopolysaccharide, inflammatory cytokines, free radicals, and ionizing radiation.