MEST Products

Description

This gene encodes a member of the [alpha]/[beta] hydrolase fold family and has isoform specific imprinting. The loss of imprinting of this gene has been linked to certain types of cancer and may be due to promotor switching. The encoded protein may play a role in development. Three transcript variants encoding two distinct isoforms have been identified for this gene. A pseudogene for this locus is located on chromosome 6. [provided by RefSeq]. Transcript Variant: This variant (2) contains a distinct 5' UTR and lacks an in-frame portion of the 5' coding region, compared to variant 1. The resulting isoform (b) has a shorter N-terminus when compared to isoform a. This isoform (b) is biallelically expressed. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Bioinformatics

Product By Gene ID	4232
Alternate Names	DKFZp686L18234 EC 3.- mesoderm specific transcript (mouse) homolog mesoderm specific transcript homolog (mouse) mesoderm-specific transcript homolog protein MGC111102 MGC8703 paternally expressed gene 1 PEG1Paternally-expressed gene 1 protein

Research Areas for MEST

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Cell Biology