Mesothelin Products

Antibodies
Mesothelin Antibody (420404) ...
Mesothelin Antibody (420404) [Unco...
MAB32651
Species: Hu
Applications: IHC
Host: Rat Monoclonal
Formulation Catalog # Availability Price  
ELISA Kits
Human Mesothelin Quantikine E ...
Human Mesothelin Quantikine ELISA Kit
DMSLN0
Species: Hu
Applications: ELISA
Human Mesothelin DuoSet ELISA ...
Human Mesothelin DuoSet ELISA, 15 ...
DY3265
Species: Hu
Applications: ELISA
Human Mesothelin Propeptide/M ...
Human Mesothelin Propeptide/MPF Du...
DY3448
Species: Hu
Applications: ELISA
Lysates
Mesothelin Overexpression Lys ...
Mesothelin Overexpression Lysate
NBL1-13332
Species: Hu
Applications: WB, ELISA
Proteins
Recombinant Human Mesothelin ...
Recombinant Human Mesothelin (aa 2...
3265-MS
Species: Hu
Applications: Bioactivity
Formulation Catalog # Availability Price  
Recombinant Human Mesothelin ...
Recombinant Human Mesothelin (aa 3...
10093-MS
Species: Hu
Applications: Bioactivity
Formulation Catalog # Availability Price  
Recombinant Mouse Mesothelin ...
Recombinant Mouse Mesothelin (aa 2...
8604-MS
Species: Mu
Applications: Bioactivity
Formulation Catalog # Availability Price  

Description

MSLN, also known as Mesothelin, has 4 isoforms, a 630 amino acid isoform that is 69 kDa, a 622 amino acid isoform that is 68 kDa, a 656 amino acid isoform that is 71 kDa, and a 621 amino acid isoform that is 68 kDa, expressed in lung, heart, placenta kidney, and overexpressed in mesotheliomas, ovarian cancers, and some squamous cell carcinomas. Membrane-anchored forms may play a role in cellular adhesion and megakaryocyte-potentiating factor (MPF) potentiates megakaryocyte colony formation in vitro. Current research is being performed on several diseases and disorders including squamous cell carcinoma, ovarian cancer, carcinoma, malignant biphasic mesothelioma, bile duct adenoma, malignant mesothelioma, malignant pleural mesothelioma, gastrointestinal stromal tumor, renal clear cell carcinoma, epithelioid sarcoma, benign mesothelioma, pancreatic ductal adenocarcinoma, asbestosis, pancreatic ductal carcinoma, thymic carcinoma, acute myeloid leukemia, epithelial ovarian cancer, myeloid leukemia, thoracic cancer, and pancreatitis. This protein has also shown an interaction with MUC16 and RSG1 in cell adhesion and pancreas development processes and pathways.

Bioinformatics

Entrez Human
Uniprot Human
Human
Human
Human
Product By Gene ID 10232
Alternate Names
  • soluble MPF mesothelin related protein
  • CAK1 antigen
  • megakaryocyte potentiating factor
  • Pre-pro-megakaryocyte-potentiating factor
  • MPFSMRP
  • CAK1
  • mesothelin

Research Areas for Mesothelin

Find related products by research area and learn more about each of the different research areas below.

Cancer

PTMs for Mesothelin

Learn more about PTMs related to Mesothelin.

Cleavage
Methylation

Bioinformatics Tool for Mesothelin

Discover related pathways, diseases and genes to Mesothelin. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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