MEK1 Products

Antibodies
MEK1 Antibody (1F5)
MEK1 Antibody (1F5)
Species: Hu
Applications: WB, ICC/IF, IHC, IHC-P
Host: Mouse Monoclonal
MEK1 [p Thr292] Antibody
MEK1 [p Thr292] Antibody
NB500-145
Species: Hu, Bovine, Canine, Primate, Mouse, Rat
Applications: WB
Host: Rabbit Polyclonal
MEK1 Antibody (239416) [Uncon ...
MEK1 Antibody (239416) [Unconjugated]
MAB2678
Species: Hu, Mu, Rt
Applications: WB, Simple Western, ICC
Host: Mouse Monoclonal
ELISA Kits
MEK1 [p Ser217, p Ser221] ELI ...
MEK1 [p Ser217, p Ser221] ELISA Ki...
KA2165
Species: Hu, Mu, Rt
MEK1 [p Ser217, p Ser221] ELI ...
MEK1 [p Ser217, p Ser221] ELISA Ki...
KA2166
Species: Hu, Mu, Rt
Lysates
MEK1 Overexpression Lysate (N ...
MEK1 Overexpression Lysate (Native)
NBL1-12845
Applications: WB
Proteins
MEK1 Partial Recombinant Prot ...
MEK1 Partial Recombinant Protein
H00005604-Q01
Species: Hu
Applications: WB, ELISA, PA
MEK1 Recombinant Protein Anti ...
MEK1 Recombinant Protein Antigen
NBP1-87790PEP
Species: Hu
Applications: AC
RNAi
MEK1 RNAi
MEK1 RNAi
H00005604-R02
Species: Hu

Description

MEK 1 (MAP Kinase Kinase, also known as MKK) is an integral component of the MAP kinase cascade that regulates cell growth and differentiation (Ahn, 1993; Chong et al., 2003). This pathway also plays a key role in synaptic plasticity in brain (Adams and Sweatt, 2002). Activated MEK 1 acts as a dual specificity kinase phosphorylating both a threonine and a tyrosine residue on MAP kinase (Kyriakis et al., 1991; Seger et al., 1991; Crews et al., 1992) Conversely there also appears to be a feedback phosphorylation of MEK 1 by MAP kinase. The sites on MEK 1 that are phosphorylated by MAP kinase are Thr292 and Thr386 (Mansour et al., 1994).

Bioinformatics

Entrez Human
Mouse
Rat
Uniprot Human
Human
Human
Human
Human
Product By Gene ID 5604
Alternate Names
  • MAP kinase kinase 1
  • protein kinase, mitogen-activated, kinase 1 (MAP kinase kinase 1)
  • ERK activator kinase 1
  • dual specificity mitogen-activated protein kinase kinase 1
  • MAPKK1
  • PRKMK1EC 2.7.12.2
  • MKK1MEK 1
  • MEK1MAPKK 1
  • MAPK/ERK kinase 1
  • mitogen-activated protein kinase kinase 1

Research Areas for MEK1

Find related products by research area and learn more about each of the different research areas below.

Angiogenesis
Autophagy
Cancer
MAP Kinase Signaling
Phospho-Specific
Protein Phosphatase
Signal Transduction
Tyrosine Kinases

Bioinformatics Tool for MEK1

Discover related pathways, diseases and genes to MEK1. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
Vizit™, under license from BioVista Inc.