Species: Hu, Mu, Rt
Applications: WB, ICC/IF, IHC
Host: Mouse Monoclonal
Species: Hu, Mu, Rt, Ca, Bv, Ca, Ch, Pm, Rb, RM, Xp, Ze
Applications: WB, ICC/IF, IHC
Host: Rabbit Polyclonal
Species: Hu, Mu, Rt, Bv, Ca, Pm
Applications: WB
Host: Rabbit Polyclonal
Species: Hu
Applications: ELISA
Species: Hu
Applications: ELISA
Species: Hu
Applications: WB
Species: Hu
Applications: Enzyme Activity
Species: Hu
Applications: WB, ELISA, MA, PAGE, AP
Species: Hu
Applications: AC
Description
MEK1 and MEK2 (MAPK kinase 1/2, or ERK kinase 1/2) are mitogen-activated protein kinases that stimulate MAP kinase activity, playing a role in both cell growth and differentiation (1,2). MEK itself is activated via phosphorylation at serines 217/218 and 221/222 by upstream activator kinases, including c-raf, mos and MEK kinase (3,4). MEK1 and MEK2 are activated by a wide variety of growth factors and cytokines, and also by membrane depolarization and calcium influx (5).
Bioinformatics
| Entrez |
Human
Mouse
Rat
|
| Uniprot |
|
| Product By Gene ID |
5604 |
| Alternate Names |
- dual specificity mitogen-activated protein kinase kinase 1
- ERK activator kinase 1
- MAP kinase kinase 1
- MAP2K1
- MAPK/ERK kinase 1
- MAPKK1
- MEK1
- MEK1MAPKK 1
- mitogen-activated protein kinase kinase 1
- MKK1
- MKK1MEK 1
- PRKMK1EC 2.7.12.2
- protein kinase, mitogen-activated, kinase 1 (MAP kinase kinase 1)
|
![Western Blot MEK1 [p Thr292] Antibody - Azide Free](http://images.novusbio.com/fullsize/MEK1-[p-Thr292]-Antibody-Western-Blot-NB500-145-img0001.jpg)
![SDS-PAGE MEK1 [Unconjugated]](http://images.novusbio.com/fullsize/11584-me_recombinant-human-mek1-protein-cf-sds-page-782024151823.jpg)
