MASP2 Products

Description

The Ra-reactive factor (RARF) is a complement-dependent bactericidal factor that binds to the Ra and R2 polysaccharides expressed by certain enterobacteria. Alternate splicing of this gene results in two transcript variants encoding two RARF components that are involved in the mannan-binding lectin pathway of complement activation. The longer isoform is cleaved into two chains which form a heterodimer linked by a disulfide bond. The encoded proteins are members of the trypsin family of peptidases. [provided by RefSeq]

Bioinformatics

Uniprot	O00187 Human
Product By Gene ID	10747
Alternate Names	EC 3.4.21 EC 3.4.21.104 mannan-binding lectin serine peptidase 1 pseudogene 1 mannan-binding lectin serine peptidase 2 mannan-binding lectin serine protease 1 pseudogene 1 mannan-binding lectin serine protease 2 Mannose-binding protein-associated serine protease 2 MAP19 MASP1P1 MASP-2 MBL-associated plasma protein of 19 kD MBL-associated serine protease 2 small MBL-associated protein sMAP