MAP4K3 Products

Antibodies
MAP4K3 Antibody
MAP4K3 Antibody
NBP1-81824
Species: Hu
Applications: ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
MAP4K3 Antibody
MAP4K3 Antibody
NBP2-29955
Species: Hu
Applications: WB, Flow, IHC-P
Host: Rabbit Polyclonal
Lysates
MAP4K3 Overexpression Lysate ...
MAP4K3 Overexpression Lysate (Native)
NBL1-12860
Applications: WB
Proteins
MAP4K3 Recombinant Protein An ...
MAP4K3 Recombinant Protein Antigen
NBP1-81824PEP
Species: Hu
Applications: AC
RNAi
MAP4K3 RNAi
MAP4K3 RNAi
H00008491-R02
Species: Hu

Description

Several mammalian kinases have been identified which exhibit sequence similarity to the Saccharomyces cerevisiae serine/threonine kinase STE20. STE20 is involved in relaying signals from G-protein coupled receptors to cytosolic MAP kinase cascades, and it lies upstream of a MAP kinase kinase kinase. Mammalian STE20-like kinases include GLK, KHS, NIK, YSK1, HPK1, Krs-1, Krs-2 and human GC kinase. GLK (for GC-like kinase) is an 885 amino acid protein that shares a high degree of homology with GC kinase and HPK1. Like many of the STE20-like kinases, GLK specifically activates the JNK pathway. Epistasis studies with dominant negative mutants of MEKK1 suggest that GLK functions upstream of MEKK1 in the JNK signaling pathway.

Bioinformatics

Entrez Human
Mouse
Rat
Uniprot Human
Product By Gene ID 8491
Alternate Names
  • EC 2.7.11
  • MAPK/ERK kinase kinase kinase 3
  • germinal center kinase-like kinase
  • RAB8IPL1
  • Germinal center kinase-related protein kinase
  • EC 2.7.11.1
  • MAPKKKK3
  • GLKMEKKK 3
  • MEK kinase kinase 3
  • mitogen-activated protein kinase kinase kinase kinase 3

Research Areas for MAP4K3

Find related products by research area and learn more about each of the different research areas below.

Lipid and Metabolism
Protein Kinase

PTMs for MAP4K3

Learn more about PTMs related to MAP4K3.

Phosphorylation
Dephosphorylation

Bioinformatics Tool for MAP4K3

Discover related pathways, diseases and genes to MAP4K3. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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