Applications: WB, ELISA, ICC/IF, S-ELISA
Host: Mouse Monoclonal
Species: Hu, Mu
Applications: WB, ELISA, IHC, IHC-P
Host: Rabbit Polyclonal
MAP1 is a novel Bax-associating protein, named MAP-1 (Modulator of Apoptosis), mediates caspase-dependent apoptosis in mammalian cells when overexpressed. MAP-1 homodimerizes and associates with the proapoptotic Bax and the prosurvival Bcl-2 and Bcl-X(L) of the Bcl-2 family in vitro and in vivo in mammalian cells. These data suggest that MAP-1 mediates apoptosis through a mechanism that involves binding to Bax.
Research Areas for MAP1
Find related products by research area and learn more about each of the different research areas below.ApoptosisMAP Kinase Signaling