Species: Hu, Mu
Applications: WB
Host: Rabbit Polyclonal
Species: Mu
Applications: WB
Host: Rabbit Polyclonal
Species: Hu
Applications: WB
Host: Mouse Polyclonal
Species: Hu
Applications: WB
Description
Mannosidases are divided into two subtypes; I and II, (EC numbers 3.2.1.113 and 3.2.1.114 respectively) which display awide expression pattern. Mannosidase I hydrolyzes (1,2)-linked alpha-D-mannose residues in the oligo-mannoseoligosaccharide Man9(GlcNAc)2 and mannosidase II hydrolyzes (1,3)- and (1,6)-linked alpha-D-mannose residues inMan5(GlcNAc)3. Both subtypes require a divalent cation cofactor. Mutations in mannosidases can cause mannosidosis(mannosidase I deficiency).
Bioinformatics
Entrez |
Human |
Uniprot |
Human |
Product By Gene ID |
57134 |
Alternate Names |
- 1,2-alpha-mannosidase IC
- Alpha-1,2-mannosidase IC
- EC 3.2.1.113
- HMICProcessing alpha-1,2-mannosidase IC
- MAN1A3
- MAN1C
- Mannosidase alpha class 1C member 1
- mannosidase, alpha, class 1C, member 1
- mannosyl-oligosaccharide 1,2-alpha-mannosidase IC
- pp6318
|
Research Areas for MAN1C1
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Stem Cell Markers