MafF Products

Description

The protein encoded by the MAFF gene is a basic leucine zipper (bZIP) transcription factor that lacks a transactivation domain. It is known to bind the US-2 DNA element in the promoter of the oxytocin receptor (OTR) gene and most likely heterodimerizes with other leucine zipper-containing proteins to enhance expression of the OTR gene during term pregnancy. The encoded protein can also form homodimers, and since it lacks a transactivation domain, the homodimer may act as a repressor of transcription. This gene may also be involved in the cellular stress response. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq]

Bioinformatics

Entrez	23764 Human
Uniprot	NP_036455.1 Human Q9ULX9 Human
Product By Gene ID	23764
Alternate Names	hMafF transcription factor MafF U-MAF U-Maf v-maf avian musculoaponeurotic fibrosarcoma oncogene family protein F v-maf musculoaponeurotic fibrosarcoma (avian) oncogene family, protein F v-maf musculoaponeurotic fibrosarcoma oncogene homolog F (avian) V-maf musculoaponeurotic fibrosarcoma oncogene homolog F