Species: Hu
Applications: WB
Description
LYNX1 encodes a member of the Ly-6/neurotoxin gene family, a group of lymphocyte antigens that attach to the cell surface by a glycosylphosphatidylinositol anchor and have a unique structure showing conserved 8-10 cysteine residues with a characteristic spacing pattern. Functional analysis indicates that this protein is not a ligand or neurotransmitter but has the capacity to enhance nicotinic acetylcholine receptor function in the presence of acetylcholine. This gene may also play a role in the pathogenesis of psoriasis vulgaris. Alternatively spliced variants encoding different isoforms have been identified. [provided by RefSeq]. Transcript Variant: This variant (SLURP2) differs in the 5' UTR and in the coding region, compared to variant 1. The resulting isoform (b) is shorter, and has a distinct N-terminus when compared to isoform a.
Bioinformatics
| Entrez |
Human
|
| Uniprot |
Human
Human
Human
|
| Product By Gene ID |
66004 |
| Alternate Names |
- Ly-6 neurotoxin-like protein 1
- Ly6/neurotoxin 1
- ly-6/neurotoxin-like protein 1
- MGC40364
- secreted Ly6/uPAR related protein 2
- secreted Ly-6/uPAR-related protein 2
- SLURP2
- SLURP-2
|
