LIM Kinase 1/2 Products

Antibodies
LIM Kinase 1/2 [p Thr508, p T ...
LIM Kinase 1/2 [p Thr508, p Thr505...
NBP2-54647
Species: Hu, Rt
Applications: WB, ICC/IF, IHC-P
Host: Rabbit Polyclonal
LIM Kinase 1/2 [p Thr508] Ant ...
LIM Kinase 1/2 [p Thr508] Antibody
NBP2-54645
Species: Hu, Mu, Rt
Applications: WB, IHC, IF
Host: Rabbit Polyclonal

Description

Proteins containing LIM motifs are typically involved in cell fate determination and growth control. A family of proteins designated LIM kinases, including LIMK-1 and LIMK-2, has been identified. LIMK-1 has been shown to regulate the stabilization of F-Actin structures and cofilin activity, indicating that LIMK-1 plays a role in a signaling pathway involved in the regulation of cell motility and morphogenesis. LIMK-1 inhibits neuronal differentiation of PC12 cells, and is thought to act by interfering with events downstream of MAPK activation. Expression patterns of LIMK-1 and LIMK-2 suggest that these proteins may have different functions during development. A truncated form of LIMK-2 has been identified in adult testis that is thought to arise from an alternative initiation exon.

Bioinformatics

Entrez Human
Human
Rat
Uniprot Human
Product By Gene ID 3984
Alternate Names
  • LIM motif-containing protein kinase
  • EC 2.7.11.1
  • LIMKLIMK-1
  • LIM domain kinase 1

Research Areas for LIM Kinase 1/2

Find related products by research area and learn more about each of the different research areas below.

Breast Cancer
Cancer
Phospho-Specific
Protein Kinase

PTMs for LIM Kinase 1/2

Learn more about PTMs related to LIM Kinase 1/2.

Phosphorylation
Dephosphorylation
Cleavage
Methylation
Oxidation
Ubiquitination

Bioinformatics Tool for LIM Kinase 1/2

Discover related pathways, diseases and genes to LIM Kinase 1/2. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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