LIAS Products

Description

LIAS is encoded by this gene belongs to the biotin and lipoic acid synthetases family. It localizes in mitochondrion and plays an important role in alpha-(+)-lipoic acid synthesis. It may also function in the sulfur insertion chemistry in lipoate biosynthesis. Alternative splicing occurs at this locus and two transcript variants encoding distinct isoforms have been identified.

Bioinformatics

Entrez	11019 Human
Uniprot	NP_006850 Human O43766 Human AAH62751.1 Human
Product By Gene ID	11019
Alternate Names	LIP1 Lip-syn EC 2.8.1.8 LASmitochondrial MGC23245 lipoic acid synthetase

Diseases related to LIAS

Discover more about diseases related to LIAS.

Diabetes Mellitus
Dental Caries
Atherosclerosis
Diabetic Nephropathy
Diabetes Mellitus, Experimental
Dental Plaque
Streptococcal Infections
Kidney Diseases
Dyslipidemias
Swine Vesicular Disease
Brain Ischemia
Diabetic Neuropathies
Immunologic Deficiency Syndromes
Hemorrhage
Hyperlipidemia
Flatulence
Microcephaly
Acidosis
Physiological Stress

Pathways for LIAS

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Virulence
Biofilm Formation
Pathogenesis
Sensitization
Hypersensitivity
Forebrain Development
Fatty Acid Oxidation

PTMs for LIAS

Learn more about PTMs related to LIAS.

Reduction
Oxidation
Phosphorylation

Bioinformatics Tool for LIAS

Discover related pathways, diseases and genes to LIAS. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.