Lck Products

Antibodies
Lck [p Tyr394] Antibody (7551 ...
Lck [p Tyr394] Antibody (755103)
MAB7500
Species: Hu
Applications: WB, ICC
Host: Mouse Monoclonal
Lck Antibody (693010)
Lck Antibody (693010)
MAB37041
Species: Hu
Applications: WB, ICC, ICFlow
Host: Mouse Monoclonal
Lck [p Tyr394] Antibody
Lck [p Tyr394] Antibody
NBP1-60894
Species: Hu, Mu, Rt
Applications: WB, ELISA, ICC/IF
Host: Rabbit Polyclonal
Antibody Pairs
Lck Antibody Pair
Lck Antibody Pair
H00003932-AP11
Species: Hu
Applications: S-ELISA
Lck Antibody Pair
Lck Antibody Pair
H00003932-PW1
Species: Hu
Applications: WB, IP
Lysates
Lck Overexpression Lysate (Na ...
Lck Overexpression Lysate (Native)
NBP2-08352
Applications: WB
Lck Overexpression Lysate (Na ...
Lck Overexpression Lysate (Native)
NBP2-09247
Applications: WB
Lck Overexpression Lysate (Na ...
Lck Overexpression Lysate (Native)
NBL1-12459
Applications: WB
Proteins
Lck Recombinant Protein Antig ...
Lck Recombinant Protein Antigen
NBP1-85804PEP
Species: Hu
Applications: AC
Lck Recombinant Protein
Lck Recombinant Protein
P4714
Species: Hu
Applications: Func, PAGE
Lck Recombinant Protein
Lck Recombinant Protein
NBP1-99486
RNAi
Lck RNAi
Lck RNAi
H00003932-R01V
Species: Hu
Applications: WB, RNAi SP
Lck RNAi
Lck RNAi
H00003932-R02
Species: Hu

Description

The human T-cell or lymphocyte specific gene Lck/p56 is a member of the Src family of non-receptors tyrosine kinase. Mostly expressed in T cells, Lck has been shown to be critical for the normal development of T lymphocytes (1). Additionally, the N-terminal region of the tyrosine kinase Lck interacts with the cytoplasmic domains of CD4 and CD8 (2). Autophosphorylation at Tyr-394 appears to be required for maximum catalytic activity (3) but it can also be suppressed by phosphorylation of the carboxyl-terminal tyrosine Tyr-505 (4).

Bioinformatics

Entrez Human
Mouse
Rat
Uniprot Human
Human
Human
Human
Human
Product By Gene ID 3932
Alternate Names
  • EC 2.7.10
  • YT16
  • Proto-oncogene Lck
  • Protein YT16
  • p56-LCK
  • tyrosine-protein kinase Lck
  • EC 2.7.10.2
  • T-lymphocyte specific protein tyrosine kinase p56lck
  • LSK
  • proto-oncogene tyrosine-protein kinase LCK
  • T cell-specific protein-tyrosine kinase
  • pp58lck
  • Lymphocyte cell-specific protein-tyrosine kinase
  • p56lck
  • Leukocyte C-terminal Src kinase
  • p56(LSTRA) protein-tyrosine kinase
  • lymphocyte-specific protein tyrosine kinase

Research Areas for Lck

Find related products by research area and learn more about each of the different research areas below.

Adaptive Immunity
CD Markers
Cell Cycle and Replication
Immunology
Phospho-Specific
Protein Kinase
Signal Transduction
Tyrosine Kinases

Bioinformatics Tool for Lck

Discover related pathways, diseases and genes to Lck. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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