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L3MBTL4, also known as Lethal(3)malignant brain tumor-like protein 4, has a 623 amino acid isoform that is 71 kDa and a short 534 amino acid that is 61 kDa, nucleus located; belongs to Putative Polycomb group (PcG), and maintains the transcriptionally repressive state of genes, probably via a modification of chromatin, rendering it heritably changed in its expressibility. There has been research revolving around the L3MBTL4 protein involvement in breast cancer. This protein is involved in transcription, DNA-dependent; regulation of transcription, DNA-dependent; and chromatin modification pathways.
