Kv11.1 Products

Antibodies
Kv11.1 Antibody
Kv11.1 Antibody
NBP2-38797
Species: Hu, Mu, Rt
Applications: IHC, IHC-P
Host: Rabbit Polyclonal
Lysates
Kv11.1 Overexpression Lysate ...
Kv11.1 Overexpression Lysate (Native)
NBP2-10603
Applications: WB
Kv11.1 Overexpression Lysate ...
Kv11.1 Overexpression Lysate (Native)
NBL1-12154
Applications: WB
Proteins
Recombinant Human Kv11.1 Prot ...
Recombinant Human Kv11.1 Protein
H00003757-Q01
Species: Hu
Applications: WB, ELISA, PA
Kv11.1 Recombinant Protein An ...
Kv11.1 Recombinant Protein Antigen
NBP2-38797PEP
Species: Hu
Applications: AC
Recombinant Human Kv11.1 Prot ...
Recombinant Human Kv11.1 Protein
H00003757-G01-10ug
Species: Hu
RNAi
Kv11.1 RNAi
Kv11.1 RNAi
H00003757-R09
Species: Hu
Applications: RNAi, RNAi SP
Kv11.1 RNAi
Kv11.1 RNAi
H00003757-R08
Species: Hu
Applications: RNAi, RNAi SP
Kv11.1 RNAi
Kv11.1 RNAi
H00003757-R07
Species: Hu
Applications: RNAi, RNAi SP

Description

Human ether-a-go-go related gene (HERG) encodes the pore-forming subunit of the delayed rectifier potassium channel IKr. There are two N-terminal splice variants of HERG include the full-length isoform 1 alpha and the shorter isoform 1 beta. Isoform 1 beta lacks the PAS motif and deactivates at a faster rate than isoform 1alpha. Residues within the C-terminal play a role in channel expression and channel gating, including voltage-dependent activation. HERG is expressed in the heart and is more abundantly expressed in the ventricles than in the atria. Mutations in the gene encoding HERG increase beat-to-beat variability and early after depolarization. These fluctuations facilitate the genesis and propagation of premature heartbeats associated with inheritable long QT syndrome type 2 and short QT syndrome type 1.

Bioinformatics

Entrez Human
Uniprot Human
Human
Human
Human
Product By Gene ID 3757
Alternate Names
  • hERG1
  • ERG1
  • ERG
  • ERG-1
  • potassium voltage-gated channel subfamily H member 2
  • Voltage-gated potassium channel subunit Kv11.1
  • ether-a-go-go-related potassium channel protein
  • Ether-a-go-go-related protein 1
  • HERG1
  • Ether-a-go-go-related gene potassium channel 1
  • erg1
  • Eag-related protein 1
  • SQT1
  • Eag homolog
  • LQT2
  • Kv11.1
  • HERGhERG-1
  • H-ERG
  • potassium voltage-gated channel, subfamily H (eag-related), member 2

Research Areas for Kv11.1

Find related products by research area and learn more about each of the different research areas below.

Neuroscience
Neurotransmission
Potassium Channels

PTMs for Kv11.1

Learn more about PTMs related to Kv11.1.

Glycosylation
Phosphorylation
Biotinylation
Reduction
Methylation

Bioinformatics Tool for Kv11.1

Discover related pathways, diseases and genes to Kv11.1. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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