KRT81 Products

Description

KRT81 is encoded by this gene is a member of the keratin gene family. As a type II hair keratin, it is a basic protein which heterodimerizes with type I keratins to form hair and nails. The type II hair keratins are clustered in a region of chromosome 12q13 and are grouped into two distinct subfamilies based on structure similarity. One subfamily, consisting of KRTHB1, KRTHB3, and KRTHB6, is highly related. The other less-related subfamily includes KRTHB2, KRTHB4, and KRTHB5. All hair keratins are expressed in the hair follicle; this hair keratin, as well as KRTHB3 and KRTHB6, is found primarily in the hair cortex. Mutations in this gene and KRTHB6 have been observed in patients with a rare dominant hair disease, monilethrix. [provided by RefSeq]

Bioinformatics

Entrez	3887 Human
Uniprot	AAH21241 Human AAH21241.1 Human
Product By Gene ID	3887
Alternate Names	ghHb1 ghHkb1 ghHKb1 Hair keratin K2.9 hard keratin, type II, 1 Hb-1 hHAKB2-1 K81 keratin 81 Keratin, hair, basic, 1MLN 137 keratin, type II cuticular Hb1 keratin-81 Keratin-81 KRTHB1HB1 Metastatic lymph node 137 gene protein MLN137 Type II hair keratin Hb1 Type-II keratin Kb21