Kindlin Products

Antibodies
Kindlin Antibody
Kindlin Antibody
NBP1-89883
Species: Hu
Applications: WB, IHC, IHC-P
Host: Rabbit Polyclonal
Kindlin Antibody
Kindlin Antibody
NB100-523
Species: Hu, Bovine, Canine, Primate, Mouse, Rat, Xenopus
Applications: WB
Host: Rabbit Polyclonal
Kindlin Antibody
Kindlin Antibody
H00055612-B01P
Species: Hu
Applications: WB, ELISA, ICC/IF
Host: Mouse Polyclonal
Antibody Pairs
Kindlin Antibody Pair
Kindlin Antibody Pair
H00055612-PW1
Species: Hu
Applications: WB, IP
Lysates
Kindlin Overexpression Lysate ...
Kindlin Overexpression Lysate (Den...
H00055612-T01
Species: Hu
Applications: WB
Kindlin Overexpression Lysate ...
Kindlin Overexpression Lysate (Nat...
NBP2-06945
Applications: WB
Proteins
Kindlin Recombinant Protein
Kindlin Recombinant Protein
H00055612-P01
Species: Hu
Applications: WB, ELISA, PA
Kindlin Partial Recombinant P ...
Kindlin Partial Recombinant Protein
H00055612-Q01
Species: Hu
Applications: WB, ELISA, PA
Kindlin Recombinant Protein A ...
Kindlin Recombinant Protein Antigen
NBP1-89883PEP
Species: Hu
Applications: AC

Description

Due to a concerted effort to identify biomarkers for lung and colon carcinomas by genome-wide transcriptional profiling, the identification and cloning of one such gene as well as two additional closely related genes was achieved. Due to the strong sequence homology to the C. elegans UNC-112 a novel gene gene was named URP1, for UNC-112 related protein. Another novel related gene, URP2 and the previously discovered MIG-2 gene was also identified. Transcriptional analysis shows that only URP1 is significantly differentially regulated, being over-expressed in 70% of the colon carcinomas and 60% of the lung carcinomas tested. Quantification of URP1 expression by qRT-PCR showed up-regulation of the gene by 60-fold in lung tumors and up to nearly 6-fold in colon tumors. Northern blot analysis of URP1 indicates that normal expression is restricted to neuromuscular tissues. In contrast, the expression of URP2 appears to be confined primarily to tissues of the immune system. URP1 has the potential to be one of the most important prognostic and diagnostic markers of colon or lung cancer.

Bioinformatics

Entrez Human
Uniprot Human
Human
Product By Gene ID 55612
Alternate Names
  • Kindlin-1
  • chromosome 20 open reading frame 42
  • Kindlerin
  • Unc-112-related protein 1
  • UNC112 related protein 1
  • Kindlin syndrome protein
  • kindlin 1
  • UNC112A
  • kindlerin
  • FLJ20116
  • C20orf42fermitin family homolog 1
  • URP1FLJ23423
  • KIND1DTGCU2
  • fermitin family homolog 1 (Drosophila)
  • fermitin family member 1

PTMs for Kindlin

Learn more about PTMs related to Kindlin.

Phosphorylation

Bioinformatics Tool for Kindlin

Discover related pathways, diseases and genes to Kindlin. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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