Kindlin Products

Kindlin Antibody
Kindlin Antibody
Species: Hu
Applications: WB, IHC, IHC-P
Host: Rabbit Polyclonal
Kindlin Antibody
Kindlin Antibody
Species: Hu
Applications: WB, ICC/IF
Host: Mouse Polyclonal
Kindlin Overexpression Lysate ...
Kindlin Overexpression Lysate
Species: Hu
Applications: WB
Recombinant Human Kindlin GST ...
Recombinant Human Kindlin GST (N-T...
Species: Hu
Applications: WB, ELISA, PA, AP
Recombinant Human Kindlin GST ...
Recombinant Human Kindlin GST (N-T...
Species: Hu
Applications: WB, ELISA, PA, AP
Kindlin Recombinant Protein A ...
Kindlin Recombinant Protein Antigen
Species: Hu
Applications: AC


Due to a concerted effort to identify biomarkers for lung and colon carcinomas by genome-wide transcriptional profiling, the identification and cloning of one such gene as well as two additional closely related genes was achieved. Due to the strong sequence homology to the C. elegans UNC-112 a novel gene gene was named URP1, for UNC-112 related protein. Another novel related gene, URP2 and the previously discovered MIG-2 gene was also identified. Transcriptional analysis shows that only URP1 is significantly differentially regulated, being over-expressed in 70% of the colon carcinomas and 60% of the lung carcinomas tested. Quantification of URP1 expression by qRT-PCR showed up-regulation of the gene by 60-fold in lung tumors and up to nearly 6-fold in colon tumors. Northern blot analysis of URP1 indicates that normal expression is restricted to neuromuscular tissues. In contrast, the expression of URP2 appears to be confined primarily to tissues of the immune system. URP1 has the potential to be one of the most important prognostic and diagnostic markers of colon or lung cancer.


Entrez Human
Uniprot Human
Product By Gene ID 55612
Alternate Names
  • C20orf42fermitin family homolog 1
  • chromosome 20 open reading frame 42
  • fermitin family homolog 1 (Drosophila)
  • fermitin family member 1
  • FLJ20116
  • Kindlerin
  • kindlerin
  • kindlin 1
  • Kindlin syndrome protein
  • Kindlin-1
  • UNC112 related protein 1
  • UNC112A
  • Unc-112-related protein 1
  • URP1FLJ23423

PTMs for Kindlin

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Bioinformatics Tool for Kindlin

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