KCNMB2 Products

Description

Chimera RNA interference (chimera RNAi) is process by which small interfering RNA/DNA chimera triggers the destruction of mRNA for the original gene.  The discovery work, design, and application of chimera RNAi has been pioneered by Professor Kaoru Saigo and Dr. Kumiko Ui-Tei at the University of Tokyo.  Chimera RNAi has many advantages over the conventional siRNAs.  First, it has been demonstrated to have reliable knock-down for over 10,000 human genes.  Because the human genome is composed of an intricate, genetic network, chimera RNAi's unique design has successfully obviated the off-target effects including microRNA-based influence.  Another advantage of the chimera RNAi technology is its effectiveness at low concentrations (0.5nM to 5nM); only mRNA is destroyed so genomic genes are not affected.  Finally, having both the sense and anti-sense strands consisting RNA/DNA chimera, it offers much greater compound stability for streamlining in vitro and in vivo assays and applications while minimizing interferon induction and other adverse reactions.

Bioinformatics

Product By Gene ID

10242

Alternate Names

BK channel subunit beta-2 BKbeta2 calcium-activated potassium channel subunit beta-2 Calcium-activated potassium channel, subfamily M subunit beta-2 Charybdotoxin receptor subunit beta-2 Hbeta2 hbeta3 k(VCA)beta-2 large conductance calcium-activated potassium channel beta 2 subunit large-conductance Ca2+-activated K+ channel beta2 subunit Maxi K channel subunit beta-2 MaxiK channel beta 2 subunit MGC22431 potassium large conductance calcium-activated channel, subfamily M, beta member2 slo-beta-2

Research Areas for KCNMB2

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Neuroscience