KCNB1 Products

Description

Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shab-related subfamily. This member is a delayed rectifier potassium channel and its activity is modulated by some other family members. (provided by RefSeq)

Bioinformatics

Entrez	3745 Human 16500 Mouse 25736 Rat
Uniprot	NP_004966.1 Human NM_004975 Human P15387 Rat
Product By Gene ID	3745
Alternate Names	Kv2.1 potassium voltage-gated channel subfamily B member 1 h-DRK1 potassium channel protein DRK1 DRK1 h-DRK1 K(+) channel Voltage-gated potassium channel subunit Kv2.1 delayed rectifier potassium channel Kv2.1 Delayed rectifier potassium channel 1 KV2.1 potassium voltage-gated channel, Shab-related subfamily, member 1

Diseases related to KCNB1

Discover more about diseases related to KCNB1.

Hypoxia
Pathologic Vasoconstriction
Nervousness
Anoxia
Hypertensive Disease
Stenosis
Insulinoma
Diabetes Mellitus
Pulmonary Hypertension
Hypertrophy
Diabetes Mellitus, Non-insulin-dependent
Cardiomyopathies
Posttransfusion Purpura
Tissue Adhesions
Cardiac Arrhythmia
Globus Hystericus
Rheumatoid Arthritis
Liver Carcinoma
Long Qt Syndrome
Arthritis

Pathways for KCNB1

View related products by pathway and learn more about each of the pathways below.

Localization
Secretion
Insulin Secretion
Exocytosis
Membrane Depolarization
Membrane Repolarization
Vasoconstriction
Cell Death
Cell Migration
Myelination
Cell Motility
Cell Proliferation
Cell Adhesion
Transport
Cell Growth
Regulation Of Membrane Repolarization
Hyperphosphorylation
Gene Silencing
Electron Transport
Protein Targeting

PTMs for KCNB1

Learn more about PTMs related to KCNB1.

Phosphorylation
Dephosphorylation
Oxidation
Sumoylation
Biotinylation

Bioinformatics Tool for KCNB1

Discover related pathways, diseases and genes to KCNB1. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.