Potassium channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Four sequence-related potassium channel genes, shaker, shaw, shab, and shal, have been identified in Drosophila, and each has been shown to have human homolog(s). KCNA10 encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. This member contains six membrane-spanning domains with a shaker-type repeat in the fourth segment. It is specifically regulated by cGMP and postulated to mediate the effects of substances that increase intracellular cGMP.
|Product By Gene ID
- potassium voltage-gated channel subfamily A member 10
- cyclic GMP gated potassium channel
- Voltage-gated potassium channel subunit Kv1.8
- potassium voltage-gated channel, shaker-related subfamily, member 10
Pathways for KCNA10
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