JTB Products

Antibodies
JTB Antibody
JTB Antibody
NBP1-81746
Species: Hu
Applications: WB, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
JTB Antibody (4E7)
JTB Antibody (4E7)
H00010899-M02
Species: Hu
Applications: WB, ELISA
Host: Mouse Monoclonal
JTB Antibody
JTB Antibody
H00010899-B01P
Species: Hu
Applications: WB, ELISA
Host: Mouse Polyclonal
Lysates
JTB Overexpression Lysate (De ...
JTB Overexpression Lysate (Denatured)
H00010899-T01
Species: Hu
Applications: WB
JTB Overexpression Lysate (Na ...
JTB Overexpression Lysate (Native)
NBL1-12112
Applications: WB
Proteins
JTB Recombinant Protein Antig ...
JTB Recombinant Protein Antigen
NBP1-81746PEP
Species: Hu
Applications: AC
JTB Recombinant Protein
JTB Recombinant Protein
NBP2-51795
Species: Hu
Applications: PAGE
RNAi
JTB RNAi
JTB RNAi
H00010899-R01
Species: Hu
Applications: RNAi, RNAi SP

Description

JTB, also known as Protein JTB, has a 146 amino acid long isoform that is 16 kDa and a short 117 amino acid that is 13 kDa; needed for normal cytokinesis during mitosis, participates in the regulation of cell proliferation, may be a component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly, fosters AURKB activity, its overexpression induces swelling of mitochondria and reduces mitochondrial membrane potential. Disease research is currently being studied with relation to JTB and lymph node tuberculosis, tuberculous meningitis, abdominal tuberculosis, prostatitis, hepatocellular carcinoma, carcinoma, and adenoid cystic carcinoma. The protein has been shown to interact with AURKA, AURKB, BIRC5, INCENP, and LIG3 proteins in apoptotic process, regulation of cell proliferation, cell cycle cytokinesis, mitosis, and cell cycle pathways.

Bioinformatics

Entrez Human
Uniprot Human
Human
Human
Human
Product By Gene ID 10899
Alternate Names
  • PAR
  • PAR protein
  • Prostate androgen-regulated protein
  • protein JTB
  • Jumping translocation breakpoint protein
  • HSPC222
  • hJT
  • HJTB
  • jumping translocation breakpoint

Research Areas for JTB

Find related products by research area and learn more about each of the different research areas below.

Cancer

PTMs for JTB

Learn more about PTMs related to JTB.

Phosphorylation
Cleavage
Myristoylation

Bioinformatics Tool for JTB

Discover related pathways, diseases and genes to JTB. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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