JNK/JIP3 Products

Description

The protein encoded by this gene shares similarity with the product of Drosophila syd gene, required for the functional interaction of kinesin I with axonal cargo. Studies of the similar gene in mouse suggested that this protein may interact with, and regulate the activity of numerous protein kinases of the JNK signaling pathway, and thus function as a scaffold protein in neuronal cells. The C. elegans counterpart of this gene is found to regulate synaptic vesicle transport possibly by integrating JNK signaling and kinesin-1 transport. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined.

Bioinformatics

Entrez	23162 Human 30957 Mouse
Uniprot	NP_055948 Human
Product By Gene ID	23162
Alternate Names	C-jun-amino-terminal kinase interacting protein 3 C-Jun-amino-terminal kinase-interacting protein 3 DKFZp762N1113 homolog of Drosophila Sunday driver 2 JIP-3 JIP3FLJ00027 JNK MAP kinase scaffold protein 3 JNK/SAPK-associated protein-1 JNK/stress-activated protein kinase-associated protein 1 JNK-interacting protein 3 JSAP1 KIAA1066SYD2 mitogen-activated protein kinase 8 interacting protein 3 Mitogen-activated protein kinase 8-interacting protein 3 syd