Jak2 Products

Antibodies
Jak2 Antibody
Jak2 Antibody
NBP1-22975
Species: Hu, Canine, Equine, Ferret, Primate, Rhesus Macaque
Applications: WB, ICC/IF, IHC, IHC-P, IP
Host: Rabbit Polyclonal
Jak2 Antibody
Jak2 Antibody
NBP1-61916
Species: Hu, Mu, Rt
Applications: WB, ELISA, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
Jak2 Antibody
Jak2 Antibody
AF2988
Species: Mu, Rt
Applications: WB
Host: Goat Polyclonal
Proteins
Jak2 Recombinant Protein Anti ...
Jak2 Recombinant Protein Antigen
NBP2-38476PEP
Species: Hu
Applications: AC
Jak2 Recombinant Protein
Jak2 Recombinant Protein
NBP2-23154
Species: Hu
Applications: PAGE
RNAi
Jak2 RNAi
Jak2 RNAi
H00003717-R02
Species: Hu

Description

Jak2 is a member of the Janus family tyrosine kinases (Jaks), whose function is to transduce extracellular signals from cytokines and interferons. Jaks associate with cytokine receptors; upon ligand binding, Jaks phosphorylate the receptor. The phosphorylated receptors are bound by SH2-containing proteins, one class of which is the signal transducers and activators of transcription (STATs). Activated STATs, then, translocate to the nucleus to mediate gene transcription (1,2). Tyr1007/1008 of Jak2 are the homologous Tyr1054/1055 in Tyk2, and phosphorylation at these residues is needed for Tyk2 activation (3). A chromosomal aberration involving Jak2 is found in a form of pre-B acute myeloid leukemia (4).

Bioinformatics

Entrez Human
Mouse
Rat
Uniprot Human
Human
Human
Human
Human
Human
Product By Gene ID 3717
Alternate Names
  • EC 2.7.10.2
  • EC 2.7.10
  • JAK-2
  • tyrosine-protein kinase JAK2
  • JTK10
  • Janus kinase 2Janus kinase 2 (a protein tyrosine kinase)

Research Areas for Jak2

Find related products by research area and learn more about each of the different research areas below.

Cell Cycle and Replication
Phospho-Specific
Signal Transduction

Bioinformatics Tool for Jak2

Discover related pathways, diseases and genes to Jak2. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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