Species: Hu, Mu, Rt
Applications: WB, ELISA, ICC/IF, IHC, IP
Host: Rabbit Polyclonal
Species: Mu, Rt
Applications: WB, IHC
Host: Rabbit Polyclonal
Species: Hu, Mu
Applications: WB, ICC/IF
Host: Rabbit Polyclonal
Species: Hu
Applications: WB
Species: Hu
Applications: AC
Description
Regulates inositol phosphate metabolism by phosphorylation of second messenger inositol 1,4,5-trisphosphate to Ins(1,3,4,5)P4. The activity of the inositol 1,4,5-trisphosphate 3-kinase is responsible for regulating the levels of a large number of inositol polyphosphates that are important in cellular signaling. Both calcium/calmodulin and protein phosphorylation mechanisms control its activity. It is also a substrate for the cyclic AMP-dependent protein kinase, calcium/calmodulin- dependent protein kinase II, and protein kinase C in vitro. ITPKA and ITPKB are 68% identical in the C-terminus region. (provided by RefSeq)
Bioinformatics
| Entrez |
Human
|
| Uniprot |
Human
Human
|
| Product By Gene ID |
3706 |
| Alternate Names |
- EC 2.7.1.127
- inositol 14,5-trisphosphate 3-kinase AIP3 3-kinase A
- inositol-trisphosphate 3-kinase A
- InsP 3-kinase A
- IP3-3KA
- IP3K A
- IP3KA
|
