ITPKA Products

Description

Regulates inositol phosphate metabolism by phosphorylation of second messenger inositol 1,4,5-trisphosphate to Ins(1,3,4,5)P4. The activity of the inositol 1,4,5-trisphosphate 3-kinase is responsible for regulating the levels of a large number of inositol polyphosphates that are important in cellular signaling. Both calcium/calmodulin and protein phosphorylation mechanisms control its activity. It is also a substrate for the cyclic AMP-dependent protein kinase, calcium/calmodulin- dependent protein kinase II, and protein kinase C in vitro. ITPKA and ITPKB are 68% identical in the C-terminus region. (provided by RefSeq)

Bioinformatics

Product By Gene ID	3706
Alternate Names	EC 2.7.1.127 inositol 14,5-trisphosphate 3-kinase AIP3 3-kinase A inositol-trisphosphate 3-kinase A InsP 3-kinase A IP3-3KA IP3K A IP3KA

Research Areas for ITPKA

Find related products by research area and learn more about each of the different research areas below.

Neuroscience
Signal Transduction