INSRR/IR-related receptor Products

Antibodies
INSRR/IR-related receptor Ant ...
INSRR/IR-related receptor Antibody
AF3055
Species: Hu
Applications: WB, IHC
Host: Goat Polyclonal
Conjugate Catalog # Availability Size Price
INSRR/IR-related receptor Ant ...
INSRR/IR-related receptor Antibody...
MAB30551
Species: Hu
Applications: WB
Host: Mouse Monoclonal
INSRR/IR-related receptor Ant ...
INSRR/IR-related receptor Antibody...
MAB3055
Species: Hu
Applications: WB, Flow
Host: Mouse Monoclonal
Lysates
INSRR/IR-related receptor Ove ...
INSRR/IR-related receptor Overexpr...
NBP2-10334
Applications: WB
Proteins
INSRR/IR-related receptor Par ...
INSRR/IR-related receptor Partial ...
H00003645-Q01
Species: Hu
Applications: WB, ELISA, PA
INSRR/IR-related receptor Rec ...
INSRR/IR-related receptor Recombin...
NBP1-87704PEP
Species: Hu
Applications: AC
RNAi
INSRR/IR-related receptor RNA ...
INSRR/IR-related receptor RNAi
H00003645-R04
Species: Hu
Applications: RNAi, RNAi SP

Description

The insulin receptor related receptor (IRR) is a heterotetrameric transmembrane receptor composed of two alpha and 2 beta chains linked by disulfide bonds. The alpha chains contribute to the formation of the ligand-binding domain, while the beta chains carry the kinase domain. Member of the insulin RTK family, IRR shares high homology with the insulin (IR) and the insulin-like growth factor-1 receptor (IGF-1R), but doesn't bind any of IR and IGF-1R known ligands (1-2). In contrast to the widespread patterns of expression to IR and IGF-1R, IRR demonstrates a very restricted cellular distribution in a subset of tissues of neuronal origin and its biological functions are still unknown (3).

Bioinformatics

Entrez Human
Uniprot Human
Human
Product By Gene ID 3645
Alternate Names
  • EC 2.7.10
  • insulin receptor-related protein
  • EC 2.7.10.1
  • IRRIR-related receptor
  • insulin receptor-related receptor

Pathways for INSRR/IR-related receptor

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Methylation
Insulin Secretion
Dna Methylation
Cell Growth
Localization
Glycolysis
Secretion

Research Areas for INSRR/IR-related receptor

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Protein Kinase

PTMs for INSRR/IR-related receptor

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Phosphorylation
Methylation

Bioinformatics Tool for INSRR/IR-related receptor

Discover related pathways, diseases and genes to INSRR/IR-related receptor. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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