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Imidazoquinoline Resiquimod (R-848), TLR7 and TLR8 ligand Products


Description

Imidazoquinoline Resiquimod (R-848), TLR7 and TLR8 ligand is a low molecular weight synthetic molecule of the Imidazoquinoline family. It has potent immunostimulatory activity. It stimulates antibody secretion, cytokine production, protection from apoptosis and CD80 up-regulation. R-848 has been shown to activate only TLR7 and TLR8. This activation is MyD88 dependent and leads to the induction of the transcription factor NF-kB.

Bioinformatics

Alternate Names
  • 4-Amino-2-(ethoxymethyl)-a,a-dimethyl-1H-imidazo[4,5-c]quinoline-1-ethanol
  • Imidazoquinoline Resiquimod (R-848),TLR7 & TLR8 ligand
  • Imidazoquinoline Resiquimod R-848
  • Imidazoquinoline Resiquimod
  • R-848
  • Resiquimod
  • S 28463