IkB-beta Products

Antibodies
IkB-beta Antibody (347428)
IkB-beta Antibody (347428)
MAB3425
Species: Hu, Rt
Applications: WB
Host: Mouse Monoclonal
Formulation Catalog # Availability Price  
IkB-beta Antibody (SN0648)
IkB-beta Antibody (SN0648)
NBP2-67645
Species: Hu
Applications: WB, ICC/IF, IHC, IHC-P, IP
Host: Rabbit Monoclonal
IkB-beta Antibody
IkB-beta Antibody
AF5225
Species: Hu, Mu
Applications: WB
Host: Goat Polyclonal
Formulation Catalog # Availability Price  
Lysates
IkB-beta Overexpression Lysat ...
IkB-beta Overexpression Lysate
NBL1-13621
Species: Hu
Applications: WB
Proteins
Recombinant Human IkB-beta Hi ...
Recombinant Human IkB-beta His Pro...
NBP1-99091
Species: Hu
Applications: PAGE
IkB-beta Recombinant Protein ...
IkB-beta Recombinant Protein Antigen
NBP2-57108PEP
Species: Hu
Applications: AC

Description

NFKB1 (MIM 164011) or NFKB2 (MIM 164012) is bound to REL (MIM 164910), RELA (MIM 164014), or RELB (MIM 604758) to form the NFKB complex. The NFKB complex is inhibited by I-kappa-B proteins (NFKBIA, MIM 164008, or NFKBIB), which inactivate NF-kappa-B by trapping it in the cytoplasm. Phosphorylation of serine residues on the I-kappa-B proteins by kinases (IKBKA, MIM 600664 or IKBKB, MIM 603258) marks them for destruction via the ubiquitination pathway, thereby allowing activation of the NF-kappa-B complex. Activated NFKB complex translocates into the nucleus and binds DNA at kappa-B-binding motifs such as 5-prime GGGRNNYYCC 3-prime or 5-prime HGGARNYYCC 3-prime (where H is A, C, or T; R is an A or G purine; and Y is a C or T pyrimidine).[supplied by OMIM]

Bioinformatics

Entrez Mouse
Human
Rat
Uniprot Human
Human
Human
Human
Product By Gene ID 4793
Alternate Names
  • beta
  • IkappaBbeta
  • I-kappa-B-beta
  • IkB-B
  • ikB-B
  • IkB-beta
  • IKBBikB-beta
  • NF-kappa-B inhibitor beta
  • NF-kappa-BIB
  • nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor
  • Thyroid receptor-interacting protein 9
  • TR-interacting protein 9
  • TRIP-9
  • TRIP9ikappaBbeta

Research Areas for IkB-beta

Find related products by research area and learn more about each of the different research areas below.

Immunology
Innate Immunity
Phospho-Specific

PTMs for IkB-beta

Learn more about PTMs related to IkB-beta.

Phosphorylation

Bioinformatics Tool for IkB-beta

Discover related pathways, diseases and genes to IkB-beta. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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