IGFALS/ALS Products

Description

The protein encoded by the IGFALS gene is a serum protein that binds insulin-like growth factors, increasing their half-life and their vascular localization. Production of the encoded protein, which contains twenty leucine-rich repeats, is stimulated by growth hormone. Defects in this gene are a cause of acid-labile subunit deficiency, which maifests itself in a delayed and slow puberty. Three transcript variants encoding two different isoforms have been found for this gene. (provided by RefSeq)

Bioinformatics

Entrez	3483 Human
Uniprot	AAH25681.1 Human NM_004970 Human P35858 Human P70389 Mouse
Product By Gene ID	3483
Alternate Names	ALS insulin-like growth factor binding protein complex acid labile chain ALS insulin-like growth factor binding protein, acid labile subunit insulin-like growth factor-binding protein complex acid labile subunit