htrA4 Products

Description

htrA4 encodes a member of the HtrA family of proteases. The encoded protein contains a putative signal peptide, an insulin growth factor binding domain, a Kazal protease inhibitor domain, a conserved trypsin domain and a PDZ domain. Based on studies on other related family members, this enzyme may function as a secreted oligomeric chaperone protease to degrade misfolded secretory proteins. Other human HtrA proteins have been implicated in arthritis, tumor suppression, unfolded stress response, apoptosis, and aging. [provided by RefSeq]

Bioinformatics

Entrez	203100 Human
Uniprot	AAH57765 Human AAH57765.1 Human NM_153692 Human P83105 Human
Product By Gene ID	203100
Alternate Names	EC 3.4.21 EC 3.4.21.- EC 3.4.21.108 FLJ90724 HtrA serine peptidase 4 probable serine protease HTRA4